Police have released some information about the crash on Route 219 south of Lewis Run late Friday morning.
They say a car was traveling north when it went out of control, went off the road and hit a tree.
Police did not identify the people, but say both of them were taken to BRMC and then taken by helicopter to out-of-town hospitals for further treatment.
They say neither occupant was wearing a seat belt.
Lewis Run Fire Police closed Route 219 at Lafayette Avenue.
Lafayette Township Volunteer Fire Department photos